Functional estrogen receptor alpha promoter polymorphism is associated with improved endothelial-dependent vasolidation.

Functional estrogen receptor alpha promoter polymorphism is associated with improved endothelial-dependent vasolidation.

Estrogen receptor alpha (ERalpha) mediates beneficial actions on endothelial nitric oxide synthase (eNOS) and cholesterol metabolism. Genetic variations in the promoter of the ERalpha may therefore influence vascular function. We have identified a single nucleotide polymorphism (T>C) in the t...

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Bibliografiske detaljer
Main Authors:	Figtree, G, Guzik, T, Robinson, BG, Channon, K, Watkins, H
Format:	Journal article
Sprog:	English
Udgivet:	2010

Lignende værker

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af: Oreffo, R, et al.
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af: Kusec, V, et al.
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