Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B and an analogue

The asymmetric synthesis of the marine sponge natural products R-strongylodiols A R-1 and B R-2, using a minimum protection strategy, is described. Two approaches were examined and the Noyori asymmetric reduction of ynones was found to be successful for installing the chirality of the natural produc...

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Bibliographic Details
Main Authors: Kirkham, J, Courtney, T, Lee, V, Baldwin, J
Format: Journal article
Language:English
Published: 2005

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