Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus.

OBJECTIVE: The common single nucleotide polymorphism (SNP) rs143383 in the 5' untranslated region (5'UTR) of growth and differentiation factor 5 (GDF5) is strongly associated with osteoarthritis (OA) and influences GDF5 allelic expression in vitro and in the joint tissues of OA patients....

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Huvudupphovsmän:	Dodd, A, Rodriguez-Fontenla, C, Calaza, M, Carr, A, Gomez-Reino, J, Tsezou, A, Reynard, L, Gonzalez, A, Loughlin, J
Materialtyp:	Journal article
Språk:	English
Publicerad:	2011

Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus av Dodd, A, Rodriguez-Fontenla, C, Calaza, M, Carr, A, Gomez-Reino, J, Tsezou, A, Reynard, L, Gonzalez, A, Loughlin, J

Publicerad 2011

Journal article

Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus.

Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus av Dodd, A, Rodriguez-Fontenla, C, Calaza, M, Carr, A, Gomez-Reino, J, Tsezou, A, Reynard, L, Gonzalez, A, Loughlin, J

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