In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem w...
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Format: | Journal article |
Language: | English |
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1996
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author | Smith, MD Wuthiekanun, V Walsh, A White, N |
author_facet | Smith, MD Wuthiekanun, V Walsh, A White, N |
author_sort | Smith, MD |
collection | OXFORD |
description | Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav. |
first_indexed | 2024-03-06T22:50:22Z |
format | Journal article |
id | oxford-uuid:5e910585-e33a-4015-ba8f-e601e6ece17b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T22:50:22Z |
publishDate | 1996 |
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spelling | oxford-uuid:5e910585-e33a-4015-ba8f-e601e6ece17b2022-03-26T17:41:34ZIn-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5e910585-e33a-4015-ba8f-e601e6ece17bEnglishSymplectic Elements at Oxford1996Smith, MDWuthiekanun, VWalsh, AWhite, NFour carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav. |
spellingShingle | Smith, MD Wuthiekanun, V Walsh, A White, N In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title | In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title_full | In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title_fullStr | In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title_full_unstemmed | In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title_short | In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei. |
title_sort | in vitro activity of carbapenem antibiotics against beta lactam susceptible and resistant strains of burkholderia pseudomallei |
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