In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.

Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem w...

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Main Authors: Smith, MD, Wuthiekanun, V, Walsh, A, White, N
Format: Journal article
Language:English
Published: 1996
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author Smith, MD
Wuthiekanun, V
Walsh, A
White, N
author_facet Smith, MD
Wuthiekanun, V
Walsh, A
White, N
author_sort Smith, MD
collection OXFORD
description Four carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav.
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spelling oxford-uuid:5e910585-e33a-4015-ba8f-e601e6ece17b2022-03-26T17:41:34ZIn-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5e910585-e33a-4015-ba8f-e601e6ece17bEnglishSymplectic Elements at Oxford1996Smith, MDWuthiekanun, VWalsh, AWhite, NFour carbapenem antibiotics were tested for their in-vitro activities (MICs, MBCs and time-kill studies) against Burkholderia pseudomallei. The carbapenems were all more active than either ceftazidime or co-amoxiclav against strains of B. pseudomallei with a normal susceptibility pattern. Biapenem was the most active antibiotic tested. All four carbapenems retained bactericidal activity against 24 strains of B. pseudomallei with reduced susceptibility to ceftazidime and/or co-amoxiclav.
spellingShingle Smith, MD
Wuthiekanun, V
Walsh, A
White, N
In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title_full In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title_fullStr In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title_full_unstemmed In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title_short In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
title_sort in vitro activity of carbapenem antibiotics against beta lactam susceptible and resistant strains of burkholderia pseudomallei
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AT walsha invitroactivityofcarbapenemantibioticsagainstbetalactamsusceptibleandresistantstrainsofburkholderiapseudomallei
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