Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

Stem cells are a central feature of metazoan biology. Haematopoietic stem cells (HSCs) represent the best-characterized example of this phenomenon, but the molecular mechanisms responsible for their formation remain obscure. The stem cell leukaemia (SCL) gene encodes a basic helix-loop-helix (bHLH)...

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Bibliographic Details
Main Authors:	Göttgens, B, Nastos, A, Kinston, S, Piltz, S, Delabesse, E, Stanley, M, Sanchez, M, Ciau-Uitz, A, Patient, R, Green, A
Format:	Journal article
Language:	English
Published:	2002

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