Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. In its severest form, choroidal neovessels breach the macular Bruch's membrane, an extracellular matrix compartment comprised of elastin and collagen laminae, and grow into the retina. We sought to determine...
Main Authors: | Chong, N, Keonin, J, Luthert, P, Frennesson, C, Weingeist, D, Wolf, R, Mullins, R, Hageman, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2005
|
Similar Items
-
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration.
by: Hageman, G, et al.
Published: (2001) -
Myopic macular Bruch’s membrane defects
by: Songhomitra Panda-Jonas, et al.
Published: (2023-02-01) -
Lipid accumulation and protein modifications of Bruch’s membrane in age-related macular degeneration
by: Li-Hui Meng, et al.
Published: (2021-05-01) -
Retinal pigment epithelium–Bruch’s membrane volume in grading of age-related macular degeneration
by: Fabian Kananen, et al.
Published: (2023-11-01) -
Measurement of TIMP-3 expression and Bruch's membrane thickness in human macula.
by: Bailey, T, et al.
Published: (2001)