Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
Host-protective caspase-1 activity must be tightly regulated to prevent pathology, but mechanisms controlling the duration of cellular caspase-1 activity are unknown. Caspase-1 is activated on inflammasomes, signaling platforms that facilitate caspase-1 dimerization and autoprocessing. Previous stud...
প্রধান লেখক: | , , , , , , , , , , , , |
---|---|
বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
Rockefeller University Press
2018
|