Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces
<b>Purpose of review</b> Here, we identify shortcomings of standard compartment-based mathematical models of cancer stem-cells, and propose a continuous formalism which includes the tumor microenvironment. <b>Recent findings</b> Stem-cell models of tumor growth have pr...
Main Authors: | Maini, P, Scott, J, Dhawan, A, Hjelmeland, A, Lathia, J, Chumakova, A, Hitomi, M, Fletcher, A, Anderson, A |
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Format: | Journal article |
Language: | English |
Published: |
Springer International Publishing
2019
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