Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.

(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme). © 2008 Wile...

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Những tác giả chính: Hodgson, D, Kaka, N
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: John Wiley and Sons 2008