Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.
(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme). © 2008 Wile...
| Autores principales: | , |
|---|---|
| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons
2008
|