Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase
A paucity of novel acting antibacterials is in development to treat the rising threat of antimicrobial resistance, particularly in Gram-negative hospital pathogens, which has led to renewed efforts in antibiotic drug discovery. Fluoroquinolones are broad-spectrum antibacterials that target DNA gyras...
Үндсэн зохиолчид: | , , , , , , , , , , , , , , , |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
National Academy of Sciences
2017
|