Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

The characterization of heterogeneous multicomponent protein complexes, which goes beyond identification of protein subunits, is a challenging task. Here we describe and apply a comprehensive method that combines a mild affinity purification procedure with a multiplexed mass spectrometry approach fo...

Повний опис

Бібліографічні деталі
Автори: Synowsky, SA, van den Heuvel, R, Mohammed, S, Pijnappel, P, Heck, A
Формат: Journal article
Мова:English
Опубліковано: 2006

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