Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

The characterization of heterogeneous multicomponent protein complexes, which goes beyond identification of protein subunits, is a challenging task. Here we describe and apply a comprehensive method that combines a mild affinity purification procedure with a multiplexed mass spectrometry approach fo...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Synowsky, SA, van den Heuvel, R, Mohammed, S, Pijnappel, P, Heck, A
التنسيق: Journal article
اللغة:English
منشور في: 2006