Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism.

BACKGROUND: We assess whether remote ischemic preconditioning (rIPC) of the recipient can modify ischemia-reperfusion (IR) injury in the donor heart following orthotopic heart transplantation from brain dead donors and to examine potential mechanisms of protection. METHODS: Sixteen pigs weighing fr...

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Bibliographic Details
Main Authors: Konstantinov, I, Li, J, Cheung, M, Shimizu, M, Stokoe, J, Kharbanda, R, Redington, A
Format: Journal article
Language:English
Published: 2005