A homeostatic clock sets daughter centriole size in flies
Centrioles are highly structured organelles whose size is remarkably consistent within any given cell type. New centrioles are born when Polo-like kinase 4 (Plk4) recruits Ana2/STIL and Sas-6 to the side of an existing “mother” centriole. These two proteins then assemble into a cartwheel, which grow...
المؤلفون الرئيسيون: | Aydogan, M, Wainman, A, Saurya, S, Steinacker, T, Caballe, A, Novak, Z, Baumbach, J, Muschalik, N, Raff, J |
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التنسيق: | Journal article |
منشور في: |
Rockefeller University Press
2018
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مواد مشابهة
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Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos.
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Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal end
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Cdk1 phosphorylates Drosophila Sas-4 to recruit Polo to daughter centrioles and convert them to centrosomes
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Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation
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An autonomous oscillator times and executes centriole biogenesis
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