Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8 T-cell responses.

Irradiated malaria sporozoites induce better protection than viable untreated sporozoites. We observed early differences between irradiated and viable untreated sporozoites in priming responses in vivo to a protective CD8 T-cell epitope, pb9, of the circumsporozoite protein of Plasmodium berghei. Sp...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Plebanski, M, Hannan, C, Behboudi, S, Flanagan, K, Apostolopoulos, V, Sinden, R, Hill, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2005