Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities.

Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities.

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Two large gene and protein superfamilies, SDR and MDR (short- and medium-chain dehydrogenases/reductases), were originally defined from analysis of alcohol and polyol dehydrogenases. The superfamilies contain minimally 82 and 25 genes, respectively, in humans, minimally 324 and 86 enzyme families wh...

Bibliografske podrobnosti
Main Authors:	Jörnvall, H, Hedlund, J, Bergman, T, Oppermann, U, Persson, B
Format:	Journal article
Jezik:	English
Izdano:	2010
Teme:	Evolution, Molecular Zinc chemistry Acyl-CoA Dehydrogenase metabolism Humans Phylogeny classification Metalloproteins Protein Conformation Butyryl-CoA Dehydrogenase genetics

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