Genetic variants predisposing most strongly to type 1 diabetes diagnosed under age 7 years lie near candidate genes that function in the immune system and in pancreatic β-cells

OBJECTIVE: Immunohistological analyses of pancreata from patients with type 1 diabetes suggest distinct autoimmune islet β-cell pathology between those diagnosed at <7 years (<7 group) and those diagnosed at age ≥13 years (≥13 group), with both B- and T-lymphocyte islet inflammation co...

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Bibliografiska uppgifter
Huvudupphovsmän: Inshaw, J, Cutler, A, Crouch, D, Wicker, L, Todd, J
Materialtyp: Journal article
Språk:English
Publicerad: American Diabetes Association 2019