Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

Disease relapse is the major cause of treatment failure after allogeneic stem cell transplantation (allo-SCT) in acute myeloid leukemia (AML). To identify AML-associated genes prognostic of AML relapse post–allo-SCT, we resequenced 35 genes in 113 adults at diagnosis, 49 of whom relapsed. Two hundre...

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Détails bibliographiques
Auteurs principaux: Quek, L, Ferguson, P, Metzner, M, Ahmed, I, Kennedy, A, Garnett, C, Jeffries, S, Walter, C, Piechocki, K, Timbs, A, Danby, R, Raghavan, M, Peniket, A, Griffiths, M, Bacon, A, Ward, J, Wheatley, K, Vyas, P, Craddock, C
Format: Journal article
Langue:English
Publié: American Society of Hematology 2016