Optimising non-viral gene delivery in a tumour spheroid model.

BACKGROUND: Our current understanding of how the unique tumour microenvironment influences the efficacy of gene delivery is limited. The current investigation systematically examines the efficiency of several non-viral gene transfer agents to transfect multicellular tumour spheroids (MCTS), an in vi...

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Detalhes bibliográficos
Principais autores: Mellor, H, Davies, L, Caspar, H, Pringle, C, Hyde, S, Gill, DR, Callaghan, R
Formato: Journal article
Idioma:English
Publicado em: 2006