Glycosylation of immunoglobulin g: role of genetic and epigenetic influences

Glycosylation of immunoglobulin g: role of genetic and epigenetic influences

Objective To determine the extent to which genetic and epigenetic factors contribute to variations in glycosylation of immunoglobulin G (IgG) in humans. Methods 76 N-glycan traits in circulating IgG were analyzed by UPLC in 220 monozygotic and 310 dizygotic twin pairs from TwinsUK. A classical twin...

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Main Authors: Menni, C, Keser, T, Mangino, M, Bell, J, Erte, I, Akmačić, I, Vučković, F, Pučić Baković, M, Gornik, O, McCarthy, M, Zoldoš, V, Spector, T, Lauc, G, Valdes, A
Formato: Journal article
Idioma:English
Publicado: Public Library of Science 2013

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