A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial).

A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial).

<p>INTRODUCTION: Malaria due to Plasmodium knowlesi is reported throughout South-East Asia, and is the commonest cause of it in Malaysia. P. knowlesi replicates every 24 h and can cause severe disease and death. Current 2010 WHO Malaria Treatment Guidelines have no recommendations for the opti...

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Dettagli Bibliografici
Autori principali:	Grigg, M, William, T, Dhanaraj, P, Menon, J, Barber, B, von Seidlein, L, Rajahram, G, Price, R, Anstey, N, Yeo, T
Natura:	Journal article
Lingua:	English
Pubblicazione:	BMJ Group 2014

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