Iteamine, the first alkaloid isolated from Itea virginica L. inflorescence.

Iteamine, the first alkaloid isolated from Itea virginica L. inflorescence.

Iteamine, o-aminobenzyl β-D-glucopyranoside, is the first alkaloid to be isolated from Itea virginica. Itea is the sole plant source of D-psicose, a rare sugar likely to be a major dietary supplement. The structure of iteamine was established by NMR and confirmed by total synthesis. Iteamine and its...

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Bibliographic Details
Main Authors: Ayers, B, Hollinshead, J, Saville, A, Nakagawa, S, Adachi, I, Kato, A, Izumori, K, Bartholomew, B, Fleet, G, Nash, R
Format: Journal article
Language:English
Published: 2014
Description
Summary:Iteamine, o-aminobenzyl β-D-glucopyranoside, is the first alkaloid to be isolated from Itea virginica. Itea is the sole plant source of D-psicose, a rare sugar likely to be a major dietary supplement. The structure of iteamine was established by NMR and confirmed by total synthesis. Iteamine and its galacto-analog (which was not found in Itea plants) showed no strong inhibition of any of the 15 glycosidases tested; unnatural galacto-iteamine was a weak inhibitor of chicken liver α-N-acetylgalactosaminidase.

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