Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
Here we identify hundreds of RNA G-quadruplex (rG4) candidates in microRNAs (miRNAs), characterize the miRNA structure and miRNA–mRNA interactions on several mammalian-conserved miRNAs, and reveal the formation of rG4s in miRNAs. Notably, we study the effect of these rG4s in cells and uncover the ro...
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Bibliographic Details
| Main Authors: |
Chan, K,
Peng, B,
Umar, M,
Chan, C,
Sahakyan, A,
Le, M,
Kwok, C |
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| Format: | Journal article
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| Language: | English |
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| Published: |
Royal Society of Chemistry
2018
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