Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs

Here we identify hundreds of RNA G-quadruplex (rG4) candidates in microRNAs (miRNAs), characterize the miRNA structure and miRNA–mRNA interactions on several mammalian-conserved miRNAs, and reveal the formation of rG4s in miRNAs. Notably, we study the effect of these rG4s in cells and uncover the ro...

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Bibliographic Details
Main Authors: Chan, K, Peng, B, Umar, M, Chan, C, Sahakyan, A, Le, M, Kwok, C
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2018

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