Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Watt, F, Didangelos, A, Sawaji, Y, Saklatvala, J
Ձևաչափ:	Conference item
Հրապարակվել է:	2006

Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
‌: Alexander, S, և այլն
Հրապարակվել է: (2007)

Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage
‌: Didangelos, A, և այլն
Հրապարակվել է: (2009)

Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis.
‌: Saklatvala, J
Հրապարակվել է: (2007)

Activin is an anti-catabolic cytokine produced by injured cartilage via release of fibroblast growth factor-2 and activation of nuclear factor kappa B
‌: Watt, F, և այլն
Հրապարակվել է: (2008)

Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
‌: Watt, F, և այլն
Հրապարակվել է: (2012)

Activin A is an anti-catabolic cytokine produced by injured cartilage via release of fibroblast growth factor-2 and activation of nuclear factor kappa B
‌: Watt, F, և այլն
Հրապարակվել է: (2009)

Anti-catabolic effect of fibroblast growth factor-2 in human articular cartilage
‌: Sawaji, Y, և այլն
Հրապարակվել է: (2009)

Dexamethasone inhibits aggrecanolysis in human articular cartilage but promotes it in porcine tissue
‌: Sawaji, Y, և այլն
Հրապարակվել է: (2009)

Articular cartilage injury rapidly activates TAK1 in chondrocytes by inducing its phosphorylation and K63-polyubiquitination
‌: Ismail, H, և այլն
Հրապարակվել է: (2017)

INTERLEUKIN 1 INDUCES AGGRECAN DEGRADATION BY HUMAN ARTICULAR CHONDROCYTES THROUGH A TAK1/MKK4/JNK2 PATHWAY WITHOUT INVOLVEMENT OF NFKB
‌: Ismail, H, և այլն
Հրապարակվել է: (2013)

JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin
‌: Han Sang, և այլն
Հրապարակվել է: (2008-05-01)

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.
‌: Sawaji, Y, և այլն
Հրապարակվել է: (2008)

The c-jun N-terminal kinase (JNK)-2 controls articular cartilage aggrecan degradation and progression of experimental osteoarthritis
‌: Ismail, H, և այլն
Հրապարակվել է: (2014)

JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis.
‌: Ismail, H, և այլն
Հրապարակվել է: (2015)

Activation of mitogen activated Protein Kinases (MAPKs) and gene induction upon explantation in articular cartilage from wild type and FGF-2(-/-) mice
‌: Chong, K, և այլն
Հրապարակվել է: (2009)

Differential inflammatory gene expression patterns in JNK2 knockout mice in response to IL1, cartilage injury and surgically induced osteoarthritis
‌: Ismail, HM, և այլն
Հրապարակվել է: (2016)

BASIC FIBROBLAST GROWTH FACTOR (bFGF) MEDIATES THE IMMEDIATE INJURY RESPONSE IN ARTICULAR CARTILAGE
‌: Vincent, T, և այլն
Հրապարակվել է: (2002)

Basic FGF mediates an immediate response of articular cartilage to mechanical injury.
‌: Vincent, T, և այլն
Հրապարակվել է: (2002)

Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
‌: Vincent, T, և այլն
Հրապարակվել է: (2006)

JNK-dependent modulation of the protease secretome profile of osteoarthritic cartilage
‌: Ismail, H, և այլն
Հրապարակվել է: (2018)

Proteomic analysis of articular cartilage shows increased type II collagen synthesis in osteoarthritis and expression of inhibin betaA (activin A), a regulatory molecule for chondrocytes.
‌: Hermansson, M, և այլն
Հրապարակվել է: (2004)

Basic fibroblast growth factor: An extracellular mechanotransducer in articular cartilage?
‌: Vincent, T, և այլն
Հրապարակվել է: (2006)

Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
‌: Vincent, T, և այլն
Հրապարակվել է: (2006)

NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
‌: Smith, C, և այլն
Հրապարակվել է: (2001)

Basic fibroblast growth factor (FGF) mediator of the immediate injury response in articular cartilage
‌: Vincent, T, և այլն
Հրապարակվել է: (2001)

Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats
‌: Gao H, և այլն
Հրապարակվել է: (2020-04-01)

NF-kappaB Signaling in Chronic Inflammatory Airway Disease
‌: Michael Schuliga
Հրապարակվել է: (2015-06-01)

Two-dimensional electrophoresis of proteins secreted from articular cartilage.
‌: Hermansson, M, և այլն
Հրապարակվել է: (2007)

Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
‌: Andreakos, E, և այլն
Հրապարակվել է: (2006)

Amygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response
‌: Zeng Q, և այլն
Հրապարակվել է: (2023-08-01)

Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
‌: McLean, C, և այլն
Հրապարակվել է: (2010)

Induction of interleukin-1 in articular cartilage by explantation and cutting.
‌: Gruber, J, և այլն
Հրապարակվել է: (2004)

NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.
‌: Cherukuri Sudhakar, և այլն
Հրապարակվել է: (2009-01-01)

Effect of Knee Arthritis Therapeutic Apparatus on Structure and NF-κB Inflammatory Pathway in Articular Cartilage of Rabbits with Knee Osteoarthritis
‌: Guangwen WU, և այլն
Հրապարակվել է: (2016-04-01)

Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations
‌: Zhifeng Zhang, և այլն
Հրապարակվել է: (2016-01-01)

Amygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response [Corrigendum]
‌: Zeng Q, և այլն
Հրապարակվել է: (2024-04-01)

Aloe Extracts Inhibit Skin Inflammatory Responses by Regulating NF-κB, ERK, and JNK Signaling Pathways in an LPS-Induced RAW264.7 Macrophages Model
‌: Wang F, և այլն
Հրապարակվել է: (2023-01-01)

Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases
‌: Bettina Sehnert, և այլն
Հրապարակվել է: (2020-07-01)

Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes.
‌: Bi Zhang, և այլն
Հրապարակվել է: (2014-01-01)

Connective tissue growth factor: matrix localisation, regulation and possible function in articular cartilage
‌: McLean, C, և այլն
Հրապարակվել է: (2010)

Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes

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