Intrapatient escape in the A*0201-restricted epitope SLYNTVATL drives evolution of human immunodeficiency virus type 1 at the population level.

The hypothesis that the intrapatient emergence of cytotoxic T-lymphocyte escape variants contributes to the evolution of human immunodeficiency virus type 1 at the population (interpatient) level was tested using the HLA-A*0201-restricted gag p17 epitope SLYNTVATL. Using a simple experimental design...

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Bibliographic Details
Main Authors: Edwards, C, Pfafferott, K, Goulder, P, Phillips, R, Holmes, E
Format: Journal article
Language:English
Published: 2005