Context dependent effects of chimeric peptide morpholino conjugates contribute to dystrophin exon-skipping efficiency

Context dependent effects of chimeric peptide morpholino conjugates contribute to dystrophin exon-skipping efficiency

We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity of morpholino phosphorodiamidate oligomers (PMOs) in dyst...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Yin, HF, Boisguerin, P, Moulton, HM, Betts, C, Seow, Y, Boutilier, J, Wang, Q, Walsh, A, Lebleu, B, Wood, MJA
التنسيق:	Journal article
اللغة:	English
منشور في:	Cell Press 2016

مواد مشابهة

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency
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Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of <it>mdx </it>mice
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