Context dependent effects of chimeric peptide morpholino conjugates contribute to dystrophin exon-skipping efficiency

Context dependent effects of chimeric peptide morpholino conjugates contribute to dystrophin exon-skipping efficiency

We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity of morpholino phosphorodiamidate oligomers (PMOs) in dyst...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Yin, HF, Boisguerin, P, Moulton, HM, Betts, C, Seow, Y, Boutilier, J, Wang, Q, Walsh, A, Lebleu, B, Wood, MJA
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Cell Press 2016

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