The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer.
The CAG repeat in exon 1 of the androgen receptor (AR) genes has been postulated as both a susceptibility allele and phenotypic modifier in BRCA1-associated breast cancers. We have analysed this repeat in a set of 178 breast cancer cases who have been selected only for age of presentation at 65 year...
Main Authors: | Given, H, Radbourne, R, Oag, H, Merritt, S, Barclay, E, Hanby, A, Lamlum, H, McGrath, J, Curran, C, Tomlinson, I |
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Format: | Journal article |
Language: | English |
Published: |
2000
|
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