An investigation into the role of methylation in mammalian X-chromosome inactivation

An investigation into the role of methylation in mammalian X-chromosome inactivation

<p>X-chromosome inactivation achieves dosage compensation of X-linked genes between male (XY) and female (XX) mammals. This process involves the down-regulation of most, but not all genes on one of the two X-chromosomes in the nucleus of each female somatic cell. The mechanism of X-inactivati...

Полное описание

Библиографические подробности
Главные авторы:	Ian., S, Simpson T. Ian
Формат:	Диссертация
Язык:	English
Опубликовано:	1999
Предметы:	Gene silencing Molecular aspects X chromosome

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