The exaptation of HERV-H: Evolutionary analyses reveal the genomic features of highly transcribed elements

HERV-H endogenous retroviruses are thought to be essential to stem cell identity in humans. We embrace several decades of HERV-H research in order to relate the transcription of HERV-H loci to their genomic structure. We find that highly transcribed HERV-H loci are younger, more fragmented, and less...

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Detalhes bibliográficos
Main Authors: Gemmell, P, Hein, J, Katzourakis, A
Formato: Journal article
Publicado em: Frontiers 2019