A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.

A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.

CD45 (leukocyte common) antigen is a hemopoietic cell-specific tyrosine phosphatase essential for antigen receptor-mediated signaling in lymphocytes. The molecule undergoes complex alternative splicing in the extracellular domain, and different patterns of CD45 splicing are associated with distinct...

Podrobná bibliografie
Hlavní autoři:	Stanton, T, Boxall, S, Hirai, K, Dawes, R, Tonks, S, Yasui, T, Kanaoka, Y, Yuldasheva, N, Ishiko, O, Bodmer, W, Beverley, P, Tchilian, E
Médium:	Journal article
Jazyk:	English
Vydáno:	2003

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