Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated Plasmodium falciparum malaria

The artemisinin-based combination therapy artemether-lumefantrine is commonly used in pregnant malaria patients. However, the effect of pregnancy-related changes on exposure is unclear and pregnancy has been associated with decreased efficacy in previous studies. This study aimed to characterize the...

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Hlavní autoři: Das, J, Rulisa, S, De Vries, P, Mens, P, Kaligirwa, N, Agaba, S, Tarning, J, Karlsson, M, Dorlo, T
Médium: Journal article
Jazyk:English
Vydáno: American Society for Microbiology 2018