Asymmetric synthesis of nortropanes via Rh-catalyzed allylic arylation
Tropane derivatives are extensively used in medicine, but catalytic asymmetric methods for their synthesis are underexplored. Here we report Rh-catalyzed asymmetric Suzuki-Miyaura type cross-coupling reactions between a racemic N-Bocnortropane-derived allylic chloride and (hetero-)aryl-boronic ester...
Päätekijät: | Zhang, Y, Goetzke, F, Christensen, K, Fletcher, SP |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
American Chemical Society
2022
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