Stress-induced release of Oct-1 from the nuclear envelope is mediated by JNK phosphorylation of lamin B1
The nuclear lamina can bind and sequester transcription factors (TFs), a function lost if the lamina is abnormal, with missing or mutant lamin proteins. We now show that TF sequestration is not all-or-nothing, but a dynamic physiological response to external signals. We show that the binding of the...
| Автори: | , , , , |
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| Формат: | Journal article |
| Опубліковано: |
Public Library of Science
2017
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