Significance of coexpression of urokinase-type plasminogen activator, and matrix metalloproteinase 3 (stromelysin) and 9 (gelatinase B) in colorectal carcinoma.
Our previous study showed that proMMP-9 was activated by MMP-3 directly, and that proMMP-3 was activated by plasmin. It was postulated that the proMMP-9 activation mechanism through the protease-protease cascade existed even in vivo. The purpose of the present study was to clarify the clinical signi...
主要な著者: | Inuzuka, K, Ogata, Y, Nagase, H, Shirouzu, K |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2000
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