Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.
Cellular immune responses play a critical role in the control of human immunodeficiency virus type 1 (HIV-1); however, the breadth of these responses at the single-epitope level has not been comprehensively assessed. We therefore screened peripheral blood mononuclear cells (PBMC) from 57 individuals...
Hoofdauteurs: | Addo, M, Yu, X, Rathod, A, Cohen, D, Eldridge, R, Strick, D, Johnston, M, Corcoran, C, Wurcel, A, Fitzpatrick, C, Feeney, M, Rodriguez, W, Basgoz, N, Draenert, R, Stone, DR, Brander, C, Goulder, P, Rosenberg, E, Altfeld, M, Walker, B |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2003
|
Gelijkaardige items
-
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.
door: Yu, X, et al.
Gepubliceerd in: (2002) -
HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection.
door: Addo, M, et al.
Gepubliceerd in: (2002) -
Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.
door: Draenert, R, et al.
Gepubliceerd in: (2003) -
Vpr is preferentially targeted by CTL during HIV-1 infection.
door: Altfeld, M, et al.
Gepubliceerd in: (2001) -
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals.
door: Addo, M, et al.
Gepubliceerd in: (2001)