Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Cellular immune responses play a critical role in the control of human immunodeficiency virus type 1 (HIV-1); however, the breadth of these responses at the single-epitope level has not been comprehensively assessed. We therefore screened peripheral blood mononuclear cells (PBMC) from 57 individuals...

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Detalhes bibliográficos
Main Authors: Addo, M, Yu, X, Rathod, A, Cohen, D, Eldridge, R, Strick, D, Johnston, M, Corcoran, C, Wurcel, A, Fitzpatrick, C, Feeney, M, Rodriguez, W, Basgoz, N, Draenert, R, Stone, DR, Brander, C, Goulder, P, Rosenberg, E, Altfeld, M, Walker, B
Formato: Journal article
Idioma:English
Publicado em: 2003

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