HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation.

Eitemau Tebyg

• Identification of a novel HLA-A24-restricted cytotoxic T-lymphocyte epitope within HIV-1 Nef.
  gan: Goulder, P, et al.
  Cyhoeddwyd: (1997)
• The role of Nef protein in the pathogenesis of HIV infection
  gan: Rajapaksa, U
  Cyhoeddwyd: (2013)
• Evolution of the HIV-1 <it>nef </it>gene in HLA-B*57 Positive Elite Suppressors
  gan: Siliciano Robert F, et al.
  Cyhoeddwyd: (2010-11-01)
• Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences
  gan: Macdonald Mahiti, et al.
  Cyhoeddwyd: (2016-03-01)
• Identification of a novel HLA-B*2705-restricted cytotoxic T-lymphocyte epitope within a conserved region of HIV-1 Nef.
  gan: Goulder, P, et al.
  Cyhoeddwyd: (1997)