In silico mutation of cysteine residues in the ligand-binding domain of an N-methyl-D-aspartate receptor.
The precise nature of redox modulation of N-methyl-d-aspartate (NMDA) receptors is still unclear, although it is thought to be related to the formation and breaking of disulfide bonds. Recent structural data demonstrated the way in which disulfide bonds in the ligand-binding core of the NR1 subunit...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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