Amino acid sensing by mTORC1: intracellular transporters mark the spot

Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartments...

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Bibliographic Details
Main Authors: Goberdhan, D, Wilson, C, Harris, A
Format: Journal article
Published: Elsevier 2016