Leukemic conversion involving RAS mutations of type 1 CALR-mutated primary myelofibrosis in a patient treated for HCV cirrhosis: a case report

Leukemic conversion involving RAS mutations of type 1 CALR-mutated primary myelofibrosis in a patient treated for HCV cirrhosis: a case report

<p>Somatic frameshift mutations in exon 9 of calreticulin (<em>CALR</em>) gene are recognized as disease drivers in primary myelofibrosis (PMF), one of the three classical Philadelphia-negative myeloproliferative neoplasms (MPNs). Type 1/type 1-like&nbsp;<em>CALR</em&g...

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Main Authors: Gurban, P, Mambet, C, Botezatu, A, Necula, LG, Neagu, AI, Matei, L, Pitica, IM, Nedeianu, S, Chivu-Economescu, M, Bleotu, C, Ataman, M, Mocanu, G, Saguna, C, Pavel, AG, Stambouli, D, Sepulchre, E, Anton, G, Diaconu, CC, Constantinescu, SN
Format: Journal article
Language:English
Published: Frontiers Media 2023

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