Severe hemolysis during primaquine radical cure of Plasmodium vivax malaria: two systematic reviews and individual patient data descriptive analyses

Primaquine (PQ) kills Plasmodium vivax hypnozoites but can cause severe hemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We conducted two systematic reviews. The first used data from clinical trials to determine the variety of definitions and frequency of hematological...

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Detalhes bibliográficos
Principais autores: Yilma, D, Groves, ES, Brito-Sousa, JD, Monteiro, WM, Chu, C, Thriemer, K, Commons, RJ, Lacerda, MVG, Price, RN, Douglas, NM
Formato: Journal article
Idioma:English
Publicado em: American Society of Tropical Medicine and Hygiene 2023