FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Mead, A, Atkinson, D, Kharazi, S, Chowdhury, O, Clark, SA, Matsuoka, S, Bouriez-Jones, T, Facchini, R, Booth, C, Woll, P, Suda, T, Nerlov, C, Jacobsen, SE
التنسيق:	Conference item
منشور في:	2014

مواد مشابهة

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
حسب: Mead, A, وآخرون
منشور في: (2017)

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
حسب: Kharazi, S, وآخرون
منشور في: (2011)

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias to Multipotent Lympho-Myeloid Progenitors
حسب: Mead, A, وآخرون
منشور في: (2011)

ROLE OF BIALLELIC C/EBPALPHA MUTATIONS AND FLT-3 ITD IN INITIATION AND MAINTENANCE OF AML
حسب: Reckzeh, K, وآخرون
منشور في: (2010)

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
حسب: Mead, A, وآخرون
منشور في: (2013)

Gilteritinib as treatment for extra-medullary relapse of FLT3-ITD acute myeloid leukemia FLT3-ITD, after allogeneic haematopoietic stem cell transplantation
حسب: R. Iannotta, وآخرون
منشور في: (2022-01-01)

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors
حسب: Adam J. Mead, وآخرون
منشور في: (2013-06-01)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
حسب: Sanjuan-Pla, A, وآخرون
منشور في: (2013)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
حسب: Sanjuan-Pla, A, وآخرون
منشور في: (2013)

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
حسب: Buza-Vidas, N, وآخرون
منشور في: (2011)

FLT3-ITD POSITIVITY IN AML; CASE SERIES
حسب: Kemal FİDAN
منشور في: (2021-11-01)

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth.
حسب: Mark C Weir, وآخرون
منشور في: (2017-01-01)

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
حسب: Giacomo Volpe, وآخرون
منشور في: (2015-01-01)

AD80 HAS HIGHER POTENCY COMPARED TO CLINICALLY USED FLT3 INHIBITORS IN FLT3-ITD AML CELLS
حسب: LBL Miranda, وآخرون
منشور في: (2023-10-01)

The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors
حسب: Yang Qiu, وآخرون
منشور في: (2023-02-01)

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
حسب: Raghuveer Singh Mali, وآخرون
منشور في: (2020-05-01)

RSK1 dependency in FLT3-ITD acute myeloid leukemia
حسب: Tim Kong, وآخرون
منشور في: (2024-11-01)

Impact of FLT3-ITD length on prognosis of acute myeloid leukemia
حسب: Song-Bai Liu, وآخرون
منشور في: (2019-01-01)

An HSP90 Inhibitor Overcomes FLT3 Inhibitor Resistance in FLT3/ITD-Positive Leukemia Cells with an N676K Mutation
حسب: Hiraku Ogata, وآخرون
منشور في: (2023-09-01)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD+ AML Cells
حسب: Panpan Feng, وآخرون
منشور في: (2022-05-01)

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
حسب: Jonathan Metts, وآخرون
منشور في: (2017-06-01)

Quizartinib: a potent and selective FLT3 inhibitor for the treatment of patients with FLT3-ITD–positive AML
حسب: Jorge Cortes
منشور في: (2024-11-01)

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
حسب: Lauren Lee, وآخرون
منشور في: (2021-01-01)

Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
حسب: Dan Xu, وآخرون
منشور في: (2022-07-01)

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML
حسب: Jarno Kivioja, وآخرون
منشور في: (2021-12-01)

The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease
حسب: Farhan Basit, وآخرون
منشور في: (2018-01-01)

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
حسب: Ruiqi Zhu, وآخرون
منشور في: (2021-05-01)

Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML
حسب: Pankit Vachhani, وآخرون
منشور في: (2016-01-01)

DNA damage on the DOCK in FLT3-ITD-driven acute myeloid leukemia
حسب: Ruchi Pandey, وآخرون
منشور في: (2019-12-01)

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia
حسب: Katharina Sies, وآخرون
منشور في: (2019-04-01)

FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
حسب: Mariko Takenokuchi, وآخرون
منشور في: (2012-10-01)

CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML
حسب: Silvia Waldeck, وآخرون
منشور في: (2020-04-01)

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
حسب: Hooriyeh Shapoorian, وآخرون
منشور في: (2021-10-01)

Epigenetic programming defines haematopoietic stem cell fate restriction
حسب: Meng, Y, وآخرون
منشور في: (2023)

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
حسب: Amit Grover, وآخرون
منشور في: (2016-03-01)

Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
حسب: Brunno Gilberto Santos de Macedo, وآخرون
منشور في: (2024-10-01)

Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia
حسب: Aoli Wang, وآخرون
منشور في: (2020-04-01)

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
حسب: Neo, W, وآخرون
منشور في: (2018)

The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
حسب: Johan, Muhammad Farid
منشور في: (2019)

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML
حسب: Silvia Masciarelli, وآخرون
منشور في: (2019-12-01)