FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Mead, A, Atkinson, D, Kharazi, S, Chowdhury, O, Clark, SA, Matsuoka, S, Bouriez-Jones, T, Facchini, R, Booth, C, Woll, P, Suda, T, Nerlov, C, Jacobsen, SE
Μορφή:	Conference item
Έκδοση:	2014

Παρόμοια τεκμήρια

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
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Έκδοση: (2017)

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
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Έκδοση: (2011)

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias to Multipotent Lympho-Myeloid Progenitors
ανά: Mead, A, κ.ά.
Έκδοση: (2011)

ROLE OF BIALLELIC C/EBPALPHA MUTATIONS AND FLT-3 ITD IN INITIATION AND MAINTENANCE OF AML
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Έκδοση: (2010)

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
ανά: Mead, A, κ.ά.
Έκδοση: (2013)

Gilteritinib as treatment for extra-medullary relapse of FLT3-ITD acute myeloid leukemia FLT3-ITD, after allogeneic haematopoietic stem cell transplantation
ανά: R. Iannotta, κ.ά.
Έκδοση: (2022-01-01)

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors
ανά: Adam J. Mead, κ.ά.
Έκδοση: (2013-06-01)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
ανά: Sanjuan-Pla, A, κ.ά.
Έκδοση: (2013)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
ανά: Sanjuan-Pla, A, κ.ά.
Έκδοση: (2013)

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
ανά: Buza-Vidas, N, κ.ά.
Έκδοση: (2011)

FLT3-ITD POSITIVITY IN AML; CASE SERIES
ανά: Kemal FİDAN
Έκδοση: (2021-11-01)

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth.
ανά: Mark C Weir, κ.ά.
Έκδοση: (2017-01-01)

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
ανά: Giacomo Volpe, κ.ά.
Έκδοση: (2015-01-01)

AD80 HAS HIGHER POTENCY COMPARED TO CLINICALLY USED FLT3 INHIBITORS IN FLT3-ITD AML CELLS
ανά: LBL Miranda, κ.ά.
Έκδοση: (2023-10-01)

The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors
ανά: Yang Qiu, κ.ά.
Έκδοση: (2023-02-01)

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
ανά: Raghuveer Singh Mali, κ.ά.
Έκδοση: (2020-05-01)

RSK1 dependency in FLT3-ITD acute myeloid leukemia
ανά: Tim Kong, κ.ά.
Έκδοση: (2024-11-01)

Impact of FLT3-ITD length on prognosis of acute myeloid leukemia
ανά: Song-Bai Liu, κ.ά.
Έκδοση: (2019-01-01)

An HSP90 Inhibitor Overcomes FLT3 Inhibitor Resistance in FLT3/ITD-Positive Leukemia Cells with an N676K Mutation
ανά: Hiraku Ogata, κ.ά.
Έκδοση: (2023-09-01)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD+ AML Cells
ανά: Panpan Feng, κ.ά.
Έκδοση: (2022-05-01)

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
ανά: Jonathan Metts, κ.ά.
Έκδοση: (2017-06-01)

Quizartinib: a potent and selective FLT3 inhibitor for the treatment of patients with FLT3-ITD–positive AML
ανά: Jorge Cortes
Έκδοση: (2024-11-01)

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
ανά: Lauren Lee, κ.ά.
Έκδοση: (2021-01-01)

Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
ανά: Dan Xu, κ.ά.
Έκδοση: (2022-07-01)

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML
ανά: Jarno Kivioja, κ.ά.
Έκδοση: (2021-12-01)

The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease
ανά: Farhan Basit, κ.ά.
Έκδοση: (2018-01-01)

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
ανά: Ruiqi Zhu, κ.ά.
Έκδοση: (2021-05-01)

Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML
ανά: Pankit Vachhani, κ.ά.
Έκδοση: (2016-01-01)

DNA damage on the DOCK in FLT3-ITD-driven acute myeloid leukemia
ανά: Ruchi Pandey, κ.ά.
Έκδοση: (2019-12-01)

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia
ανά: Katharina Sies, κ.ά.
Έκδοση: (2019-04-01)

FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
ανά: Mariko Takenokuchi, κ.ά.
Έκδοση: (2012-10-01)

CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML
ανά: Silvia Waldeck, κ.ά.
Έκδοση: (2020-04-01)

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
ανά: Hooriyeh Shapoorian, κ.ά.
Έκδοση: (2021-10-01)

Epigenetic programming defines haematopoietic stem cell fate restriction
ανά: Meng, Y, κ.ά.
Έκδοση: (2023)

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
ανά: Amit Grover, κ.ά.
Έκδοση: (2016-03-01)

Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
ανά: Brunno Gilberto Santos de Macedo, κ.ά.
Έκδοση: (2024-10-01)

Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia
ανά: Aoli Wang, κ.ά.
Έκδοση: (2020-04-01)

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
ανά: Neo, W, κ.ά.
Έκδοση: (2018)

The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
ανά: Johan, Muhammad Farid
Έκδοση: (2019)

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML
ανά: Silvia Masciarelli, κ.ά.
Έκδοση: (2019-12-01)