FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

ग्रंथसूची विवरण
मुख्य लेखकों:	Mead, A, Atkinson, D, Kharazi, S, Chowdhury, O, Clark, SA, Matsuoka, S, Bouriez-Jones, T, Facchini, R, Booth, C, Woll, P, Suda, T, Nerlov, C, Jacobsen, SE
स्वरूप:	Conference item
प्रकाशित:	2014

समान संसाधन

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
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प्रकाशित: (2017)

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
द्वारा: Kharazi, S, और अन्य
प्रकाशित: (2011)

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias to Multipotent Lympho-Myeloid Progenitors
द्वारा: Mead, A, और अन्य
प्रकाशित: (2011)

ROLE OF BIALLELIC C/EBPALPHA MUTATIONS AND FLT-3 ITD IN INITIATION AND MAINTENANCE OF AML
द्वारा: Reckzeh, K, और अन्य
प्रकाशित: (2010)

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
द्वारा: Mead, A, और अन्य
प्रकाशित: (2013)

Gilteritinib as treatment for extra-medullary relapse of FLT3-ITD acute myeloid leukemia FLT3-ITD, after allogeneic haematopoietic stem cell transplantation
द्वारा: R. Iannotta, और अन्य
प्रकाशित: (2022-01-01)

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors
द्वारा: Adam J. Mead, और अन्य
प्रकाशित: (2013-06-01)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
द्वारा: Sanjuan-Pla, A, और अन्य
प्रकाशित: (2013)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
द्वारा: Sanjuan-Pla, A, और अन्य
प्रकाशित: (2013)

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
द्वारा: Buza-Vidas, N, और अन्य
प्रकाशित: (2011)

FLT3-ITD POSITIVITY IN AML; CASE SERIES
द्वारा: Kemal FİDAN
प्रकाशित: (2021-11-01)

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth.
द्वारा: Mark C Weir, और अन्य
प्रकाशित: (2017-01-01)

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
द्वारा: Giacomo Volpe, और अन्य
प्रकाशित: (2015-01-01)

AD80 HAS HIGHER POTENCY COMPARED TO CLINICALLY USED FLT3 INHIBITORS IN FLT3-ITD AML CELLS
द्वारा: LBL Miranda, और अन्य
प्रकाशित: (2023-10-01)

The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors
द्वारा: Yang Qiu, और अन्य
प्रकाशित: (2023-02-01)

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
द्वारा: Raghuveer Singh Mali, और अन्य
प्रकाशित: (2020-05-01)

RSK1 dependency in FLT3-ITD acute myeloid leukemia
द्वारा: Tim Kong, और अन्य
प्रकाशित: (2024-11-01)

Impact of FLT3-ITD length on prognosis of acute myeloid leukemia
द्वारा: Song-Bai Liu, और अन्य
प्रकाशित: (2019-01-01)

An HSP90 Inhibitor Overcomes FLT3 Inhibitor Resistance in FLT3/ITD-Positive Leukemia Cells with an N676K Mutation
द्वारा: Hiraku Ogata, और अन्य
प्रकाशित: (2023-09-01)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD+ AML Cells
द्वारा: Panpan Feng, और अन्य
प्रकाशित: (2022-05-01)

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
द्वारा: Jonathan Metts, और अन्य
प्रकाशित: (2017-06-01)

Quizartinib: a potent and selective FLT3 inhibitor for the treatment of patients with FLT3-ITD–positive AML
द्वारा: Jorge Cortes
प्रकाशित: (2024-11-01)

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
द्वारा: Lauren Lee, और अन्य
प्रकाशित: (2021-01-01)

Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
द्वारा: Dan Xu, और अन्य
प्रकाशित: (2022-07-01)

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML
द्वारा: Jarno Kivioja, और अन्य
प्रकाशित: (2021-12-01)

The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease
द्वारा: Farhan Basit, और अन्य
प्रकाशित: (2018-01-01)

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
द्वारा: Ruiqi Zhu, और अन्य
प्रकाशित: (2021-05-01)

Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML
द्वारा: Pankit Vachhani, और अन्य
प्रकाशित: (2016-01-01)

DNA damage on the DOCK in FLT3-ITD-driven acute myeloid leukemia
द्वारा: Ruchi Pandey, और अन्य
प्रकाशित: (2019-12-01)

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia
द्वारा: Katharina Sies, और अन्य
प्रकाशित: (2019-04-01)

FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
द्वारा: Mariko Takenokuchi, और अन्य
प्रकाशित: (2012-10-01)

CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML
द्वारा: Silvia Waldeck, और अन्य
प्रकाशित: (2020-04-01)

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
द्वारा: Hooriyeh Shapoorian, और अन्य
प्रकाशित: (2021-10-01)

Epigenetic programming defines haematopoietic stem cell fate restriction
द्वारा: Meng, Y, और अन्य
प्रकाशित: (2023)

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
द्वारा: Amit Grover, और अन्य
प्रकाशित: (2016-03-01)

Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
द्वारा: Brunno Gilberto Santos de Macedo, और अन्य
प्रकाशित: (2024-10-01)

Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia
द्वारा: Aoli Wang, और अन्य
प्रकाशित: (2020-04-01)

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
द्वारा: Neo, W, और अन्य
प्रकाशित: (2018)

The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
द्वारा: Johan, Muhammad Farid
प्रकाशित: (2019)

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML
द्वारा: Silvia Masciarelli, और अन्य
प्रकाशित: (2019-12-01)