FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

Bibliografiska uppgifter
Huvudupphovsmän:	Mead, A, Atkinson, D, Kharazi, S, Chowdhury, O, Clark, SA, Matsuoka, S, Bouriez-Jones, T, Facchini, R, Booth, C, Woll, P, Suda, T, Nerlov, C, Jacobsen, SE
Materialtyp:	Conference item
Publicerad:	2014

Liknande verk

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FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
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Gilteritinib as treatment for extra-medullary relapse of FLT3-ITD acute myeloid leukemia FLT3-ITD, after allogeneic haematopoietic stem cell transplantation
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Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
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FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
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Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
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RSK1 dependency in FLT3-ITD acute myeloid leukemia
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An HSP90 Inhibitor Overcomes FLT3 Inhibitor Resistance in FLT3/ITD-Positive Leukemia Cells with an N676K Mutation
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Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD+ AML Cells
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Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
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A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
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Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
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FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML
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The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease
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FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
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Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML
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DNA damage on the DOCK in FLT3-ITD-driven acute myeloid leukemia
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Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia
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FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
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CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML
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The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
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Epigenetic programming defines haematopoietic stem cell fate restriction
av: Meng, Y, et al.
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Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
av: Amit Grover, et al.
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Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
av: Brunno Gilberto Santos de Macedo, et al.
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av: Aoli Wang, et al.
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Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
av: Neo, W, et al.
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The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
av: Johan, Muhammad Farid
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Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML
av: Silvia Masciarelli, et al.
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