FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

FLT3-ITD INDUCED MYELOPROLIFERATION CAUSES A CELL EXTRINSIC DEPLETION OF HAEMATOPOIETIC STEM CELLS

書目詳細資料
Main Authors:	Mead, A, Atkinson, D, Kharazi, S, Chowdhury, O, Clark, SA, Matsuoka, S, Bouriez-Jones, T, Facchini, R, Booth, C, Woll, P, Suda, T, Nerlov, C, Jacobsen, SE
格式:	Conference item
出版:	2014

相似書籍

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
由: Mead, A, et al.
出版: (2017)

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
由: Kharazi, S, et al.
出版: (2011)

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias to Multipotent Lympho-Myeloid Progenitors
由: Mead, A, et al.
出版: (2011)

ROLE OF BIALLELIC C/EBPALPHA MUTATIONS AND FLT-3 ITD IN INITIATION AND MAINTENANCE OF AML
由: Reckzeh, K, et al.
出版: (2010)

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
由: Mead, A, et al.
出版: (2013)

Gilteritinib as treatment for extra-medullary relapse of FLT3-ITD acute myeloid leukemia FLT3-ITD, after allogeneic haematopoietic stem cell transplantation
由: R. Iannotta, et al.
出版: (2022-01-01)

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors
由: Adam J. Mead, et al.
出版: (2013-06-01)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
由: Sanjuan-Pla, A, et al.
出版: (2013)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
由: Sanjuan-Pla, A, et al.
出版: (2013)

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
由: Buza-Vidas, N, et al.
出版: (2011)

FLT3-ITD POSITIVITY IN AML; CASE SERIES
由: Kemal FİDAN
出版: (2021-11-01)

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth.
由: Mark C Weir, et al.
出版: (2017-01-01)

Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
由: Giacomo Volpe, et al.
出版: (2015-01-01)

AD80 HAS HIGHER POTENCY COMPARED TO CLINICALLY USED FLT3 INHIBITORS IN FLT3-ITD AML CELLS
由: LBL Miranda, et al.
出版: (2023-10-01)

The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors
由: Yang Qiu, et al.
出版: (2023-02-01)

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
由: Raghuveer Singh Mali, et al.
出版: (2020-05-01)

RSK1 dependency in FLT3-ITD acute myeloid leukemia
由: Tim Kong, et al.
出版: (2024-11-01)

Impact of FLT3-ITD length on prognosis of acute myeloid leukemia
由: Song-Bai Liu, et al.
出版: (2019-01-01)

An HSP90 Inhibitor Overcomes FLT3 Inhibitor Resistance in FLT3/ITD-Positive Leukemia Cells with an N676K Mutation
由: Hiraku Ogata, et al.
出版: (2023-09-01)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD+ AML Cells
由: Panpan Feng, et al.
出版: (2022-05-01)

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
由: Jonathan Metts, et al.
出版: (2017-06-01)

Quizartinib: a potent and selective FLT3 inhibitor for the treatment of patients with FLT3-ITD–positive AML
由: Jorge Cortes
出版: (2024-11-01)

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
由: Lauren Lee, et al.
出版: (2021-01-01)

Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
由: Dan Xu, et al.
出版: (2022-07-01)

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML
由: Jarno Kivioja, et al.
出版: (2021-12-01)

The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease
由: Farhan Basit, et al.
出版: (2018-01-01)

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
由: Ruiqi Zhu, et al.
出版: (2021-05-01)

Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML
由: Pankit Vachhani, et al.
出版: (2016-01-01)

DNA damage on the DOCK in FLT3-ITD-driven acute myeloid leukemia
由: Ruchi Pandey, et al.
出版: (2019-12-01)

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia
由: Katharina Sies, et al.
出版: (2019-04-01)

FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia
由: Mariko Takenokuchi, et al.
出版: (2012-10-01)

CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML
由: Silvia Waldeck, et al.
出版: (2020-04-01)

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
由: Hooriyeh Shapoorian, et al.
出版: (2021-10-01)

Epigenetic programming defines haematopoietic stem cell fate restriction
由: Meng, Y, et al.
出版: (2023)

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
由: Amit Grover, et al.
出版: (2016-03-01)

Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
由: Brunno Gilberto Santos de Macedo, et al.
出版: (2024-10-01)

Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia
由: Aoli Wang, et al.
出版: (2020-04-01)

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
由: Neo, W, et al.
出版: (2018)

The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
由: Johan, Muhammad Farid
出版: (2019)

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML
由: Silvia Masciarelli, et al.
出版: (2019-12-01)