Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts

<p><strong>Background</strong></p> While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. <p><strong>Methods</strong></p> We compared the age-standardised mortality ratios (SMRs) of...

Full description

Bibliographic Details
Main Authors: Masraf, H, Azemeraw, T, Molla, M, Jones, CI, Bremner, S, Ngari, M, Berkley, JA, Kivaya, E, Fegan, G, Tamiru, A, Kelemework, A, Lang, T, Newport, MJ, Davey, G
Format: Journal article
Language:English
Published: Oxford University Press 2020
_version_ 1797071715710271488
author Masraf, H
Azemeraw, T
Molla, M
Jones, CI
Bremner, S
Ngari, M
Berkley, JA
Kivaya, E
Fegan, G
Tamiru, A
Kelemework, A
Lang, T
Newport, MJ
Davey, G
author_facet Masraf, H
Azemeraw, T
Molla, M
Jones, CI
Bremner, S
Ngari, M
Berkley, JA
Kivaya, E
Fegan, G
Tamiru, A
Kelemework, A
Lang, T
Newport, MJ
Davey, G
author_sort Masraf, H
collection OXFORD
description <p><strong>Background</strong></p> While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. <p><strong>Methods</strong></p> We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort. <p><strong>Results</strong></p> The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4). <p><strong>Conclusions</strong></p> Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.
first_indexed 2024-03-06T22:57:20Z
format Journal article
id oxford-uuid:60e22454-8afe-4a18-a2af-6f152fa71750
institution University of Oxford
language English
last_indexed 2024-03-06T22:57:20Z
publishDate 2020
publisher Oxford University Press
record_format dspace
spelling oxford-uuid:60e22454-8afe-4a18-a2af-6f152fa717502022-03-26T17:56:01ZExcess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohortsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:60e22454-8afe-4a18-a2af-6f152fa71750EnglishSymplectic ElementsOxford University Press2020Masraf, HAzemeraw, TMolla, MJones, CIBremner, SNgari, MBerkley, JAKivaya, EFegan, GTamiru, AKelemework, ALang, TNewport, MJDavey, G<p><strong>Background</strong></p> While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. <p><strong>Methods</strong></p> We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort. <p><strong>Results</strong></p> The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4). <p><strong>Conclusions</strong></p> Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.
spellingShingle Masraf, H
Azemeraw, T
Molla, M
Jones, CI
Bremner, S
Ngari, M
Berkley, JA
Kivaya, E
Fegan, G
Tamiru, A
Kelemework, A
Lang, T
Newport, MJ
Davey, G
Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title_full Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title_fullStr Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title_full_unstemmed Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title_short Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
title_sort excess mortality among people with podoconiosis secondary analysis of two ethiopian cohorts
work_keys_str_mv AT masrafh excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT azemerawt excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT mollam excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT jonesci excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT bremners excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT ngarim excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT berkleyja excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT kivayae excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT fegang excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT tamirua excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT kelemeworka excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT langt excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT newportmj excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts
AT daveyg excessmortalityamongpeoplewithpodoconiosissecondaryanalysisoftwoethiopiancohorts